Put a genetic variant on trial.

Evidence enters.Certainty gets challenged.

GeneCourt turns a real variant-evidence conflict into a transparent, replayable hearing. Every claim stays attached to a public source; every caveat remains on the record.

  • Extractive claims
  • Human review required
  • Deterministic replay
Case 01 / The R282Q conflict On record

Question before the court

The R282Q evidence conflict

Structural supportFunctional challengeMethod reviewPopulation context
Current recordMixedHuman review required

Verified teaching docket

Two cases. One disciplined standard.

Hear the disagreement first, then use the expert-reviewed control to calibrate what a clearer record looks like.

Calibration controlSnapshot 2026-07-17
TP53 R248Qc.743G>A

The R248Q calibration case

A TP53 missense variant with an expert-panel ClinVar classification and convergent functional evidence.

Protein
NP_000537.3:p.Arg248Gln
Condition
Li-Fraumeni syndrome

The court's rules

A verdict is never invented between citations.

  1. 01

    Enter the source

    Public records and papers are captured with identifiers, dates, and exact spans.

  2. 02

    Test the claim

    Variant, condition, model, and method scope are examined before an item is admitted.

  3. 03

    Preserve uncertainty

    The final case file separates established, disputed, contextual, and missing evidence.